“Can Gut Health Improve Chronic Musculoskeletal Pain?”

by Son’s Rehabilitation Medicine & Chiropractic Clinic in Seoul

Exploring Clinical Evidence of the Gut–Pain Connection

Over the years, chronic musculoskeletal pain has often been explained through biomechanical, neurological, or psychosocial frameworks. However, a growing body of research in functional medicine and integrative care is shedding light on an additional player: the gut microbiome.

As a physician specializing in structural alignment and orthogonal neuro-biomechanics, I acknowledge the profound role that spinal balance plays in chronic pain. Yet, I have also seen that in certain stubborn or systemic cases, improving gut health can complement orthopedic or neurologic treatments and lead to meaningful results.

Let’s explore several clinical cases and research findings that highlight this relationship.


🔹 1. Fibromyalgia and Small Intestinal Bacterial Overgrowth (SIBO)

Numerous studies have shown a strong association between fibromyalgia and SIBO or gut dysbiosis.
Patients with fibromyalgia often report bloating, IBS symptoms, and fatigue. When treated with targeted gut therapies—such as low-FODMAP diets, probiotics, or herbal antimicrobials—both digestive symptoms and musculoskeletal pain tend to improve.

📖 Pimentel et al., Gut 2012
📖 Navarro-López V, Pain Manag Nurs, 2021


🔹 2. Autoimmune Arthritis and Leaky Gut

Conditions like Rheumatoid Arthritis and Ankylosing Spondylitis have been linked to increased intestinal permeability ("leaky gut") and specific gut bacteria.

  • Dietary interventions (gluten-free, dairy-free)

  • Omega-3 supplementation

  • Probiotics

…have all shown potential to reduce joint pain and inflammatory markers such as ESR and CRP.

📖 Rashid & Ebringer, Clin Rheumatol, 2007


🔹 3. Chronic Low Back Pain with IBS-like Symptoms

Patients who suffer from chronic low back pain along with abdominal bloating or irregular bowel habits may experience simultaneous improvement in both domains when gut health is restored.
This is likely due to viscerosomatic reflexes or autonomic nervous system dysregulation triggered by gut inflammation.

📖 Jones MP et al., Pain Med 2006


🔹 4. Nonspecific Widespread Pain and Systemic Inflammation

In patients with unexplained myalgia or diffuse joint pain, gut-derived inflammation—particularly from lipopolysaccharide (LPS) leakage—can act as a silent driver.
Gut-targeted therapies have been shown to lower systemic inflammatory cytokines (e.g., IL-6, TNF-alpha) and reduce pain perception.

📖 Tilg H & Moschen AR, Nat Rev Immunol, 2014


🔹 5. Post-surgical Recovery and Pain

Some patients recovering from orthopedic surgery or injury report fatigue and pain beyond expected norms. When given gut-restoring protocols (e.g., prebiotics, fermented foods, elimination diets), their recovery often accelerates, with noticeable reductions in residual pain and inflammation.


⚖️ Final Thoughts

While structural alignment and spinal integrity remain foundational, addressing the gut microbiome can enhance outcomes—especially in cases that are:

  • Systemic rather than localized

  • Resistant to standard orthopedic or neurologic care

  • Associated with fatigue, mood disturbance, or digestive issues

In my clinical philosophy, structure and function are inseparable, and sometimes healing begins from the inside out. 

👍Consultation and Appointment Information

Son PMR & Chiropractic Clinic( 2nd floor, 229-1 Gucheonmyun-Ro, Gangdongu, Seoul, South Korea) 

by  Dr Son MD & DC 
Contact: 02-482-8875 in Seoul( +82-2-482-8875)

chson@daum.net

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