Why Caudal PDRN Injection Works for Persistent Leg Numbness

(Even when Nerve Blocks have failed)

By Dr. Son, Physiatrist & US-Licensed Chiropractor

 Are you struggling with persistent leg numbness or "pins and needles" despite receiving multiple nerve blocks? Many patients visiting Dr Son Rehabilitation Medicine & Chiropractic Clinic share this exact frustration.

If traditional steroid-based treatments haven't provided lasting relief, the answer may lie in Caudal PDRN (Polydeoxyribonucleotide) Therapy.


1. Moving Beyond "Blocking" to "Regeneration"

 Standard nerve blocks typically use steroids to suppress inflammation. While effective for acute pain, they often fail to address chronic tissue degeneration or nerve ischemia (poor blood flow).

  • The Power of PDRN: Extracted from salmon DNA, PDRN is a regenerative activator. It binds to Adenosine A2A receptors, which not only reduces chronic inflammation but also triggers the body’s internal repair system.

  • Angiogenesis (New Blood Vessel Growth): Leg numbness is often caused by a lack of oxygen to the nerves. PDRN promotes VEGF (Vascular Endothelial Growth Factor), creating new micro-vessels to nourish damaged nerves.

2. The Caudal Advantage: A Comprehensive Path

 Instead of targeting a single nerve root, the Caudal (Sacral Hiatus) approach allows the medication to flow upward through the epidural space.

  • Hydrodissection: The volume of the injection physically "washes out" inflammatory debris and gently separates internal adhesions (scar tissue) that are strangling the nerve.

  • Wider Coverage: This path ensures the PDRN reaches multiple spinal levels, making it ideal for patients with multi-level stenosis or complex disc issues.

3. Proven by Medical Evidence

 Our approach is grounded in clinical research. A notable study published in the journal Medicine (Baltimore, 2017) demonstrated that patients with lumbosacral radiculopathy—who couldn't take steroids due to conditions like diabetes—experienced a dramatic drop in pain scores (from 8/10 to 1/10) after epidural PDRN injections.

4. Why Choose Dr Son Rehabilitation Medicine & Chiropractic clinic?

 At our clinic, we don't just treat the symptom; we treat the person.

  • Safe for Everyone: Since PDRN is non-steroidal, it is a safe and excellent alternative for patients with high blood pressure or diabetes.

  • Holistic Balance: Based on my expertise in the CCMC (Cervical-Craniomandibular Complex), we evaluate your entire spinal alignment to ensure the numbness doesn't return.


"Don't settle for temporary relief. It’s time to regenerate your nerve health."

If you are tired of repetitive treatments with no results, visit us in Seoul. We are dedicated to restoring your mobility and comfort through evidence-based regenerative medicine.

👍Consultation and Appointment Information

Son PMR & Chiropractic Clinic( 2nd floor, 229-1 Gucheonmyun-Ro, Gangdongu, Seoul, South Korea) 

by  Dr Son MD & DC 
Contact: 02-482-8875 in Seoul( +82-2-482-8875)

chson@daum.net

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